A rare inherited cancer syndrome characterized by hundreds to thousands of precancerous colorectal polyps. If left untreated, affected individuals inevitably develop cancer of the colon and/or rectum at a relatively young age. The standard treatment for FAP is colon removal with an ileostomy either temporarily or permanently. There are several types of ostomy reversals that may be completed including the typically utilized J-pouch. FAP is also associated with an increased risk for cancer elsewhere in the GI tract, and cancer of the thyroid, pancreas, liver, central nervous system, brain, adrenal gland, and bile ducts. FAP is inherited in an autosomal dominant manner and caused by germline mutations in the APC gene. The risk of passing the abnormal gene from affected parent to offspring is 50% for each pregnancy.